Energy metabolism plasticity enables stemness programs
نویسندگان
چکیده
منابع مشابه
Cancer metabolism, stemness and tumor recurrence
Here, we interrogated head and neck cancer (HNSCC) specimens (n = 12) to examine if different metabolic compartments (oxidative vs. glycolytic) co-exist in human tumors. A large panel of well-established biomarkers was employed to determine the metabolic state of proliferative cancer cells. Interestingly, cell proliferation in cancer cells, as marked by Ki-67 immunostaining, was strictly correl...
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Meng-Ju Wu1,2, Yu-Syuan Chen1,2, Mi Ran Kim1,2 and Chun-Ju Chang1,2* 1Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, USA 2Center for Cancer Research, Purdue University, West Lafayette, USA *Corresponding author: Chun-Ju Chang, Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 4790...
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Deiodinases are selenoenzymes that catalyze thyroid hormones (THs) activation (type 1 and type 2, D1 and D2, respectively) or inactivation (type 3, D3). THs are essential for proper body development and cellular differentiation. Their intra- and extra-cellular concentrations are tightly regulated by deiodinases with a pre-receptorial control thus generating active or inactive form of THs. Chang...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 2012
ISSN: 0077-8923
DOI: 10.1111/j.1749-6632.2012.06487.x